Vikas Pandey

New York

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I am a scientist working at the intersection of biomedical imaging hardware, data science, and deep learning. I specialize in building imaging systems and computational pipelines that turn complex optical measurements into clinically actionable insights, and I enjoy developing state-of-the-art biophotonics computational models alongside translational research that moves these tools from the lab into real-world use.

My focus is on physics-guided deep learning models with hardware-accelerated deployment for developing efficient, user-friendly, high-impact medical technologies (Imaging Technogies) that address critical challenges in oncology such as in image-guided surgery and infectious disease diagnostics.

Research Focus & Core Expertise

  • Computational Biophotonics: Developing physics-guided neural networks, deep learning models, and advanced statistical frameworks to extract precise parameters from low-photon, high-noise functional data.

  • Advanced Optical Modalities: Designing and deploying time-resolved optical imaging, single-pixel imaging, fluorescence molecular tomography, and mesoscale light-sheet platforms for paired Near-Infrared (NIR) and Shortwave-Infrared (SWIR) imaging.

  • Translational Medical Devices: Translating complex laboratory instrumentation into certified, field-deployable clinical tools.

Recent Progress & Key Achievements

  • Open-Source Software Development: Authored and published PyFli on PyPI, an open-source Python package designed for the unified, scalable processing and analysis of Fluorescence Lifetime Imaging (FLI) data.

  • Amortized Bayesian Inference: Developed a breakthrough computational framework utilizing amortized inference for exceptionally fast and robust lifetime parameter estimation in low-photon FLI regimes.

news

Sep 09, 2026 New preprint: PyFLI: A Python Library for Simulation, Parameter Estimation, and Benchmarking in Fluorescence Lifetime Imaging is now on arXiv.
Aug 31, 2026 A new version of PyFli has released on August 31, 2026. Check pyfli.org for details and examples for implementations.
May 19, 2026 Announcing PyFli — my open-source Python package for unified, scalable processing and analysis of Fluorescence Lifetime Imaging (FLI) data, now available on PyPI.

selected publications

  1. Sci. Rep.
    SeeTB: a novel alternative to sputum smear microscopy to diagnose tuberculosis in high burden countries
    Vikas Pandey, Pooja Singh, Saumya Singh, and 8 more authors
    Scientific Reports, 2019